N-acyl
|en-ay-sil|
/ˌɛnˈeɪsɪl/
acyl group attached to nitrogen
Etymology
'N-acyl' originates from combining the chemical symbol 'N' (denoting nitrogen) with the term 'acyl', where 'acyl' ultimately comes from French 'acyle' via New Latin 'acylus' and was coined from 'acid' + the chemical suffix '-yl' to denote a radical or group.
'N-acyl' arose in 19th-century chemical nomenclature by placing the letter 'N' before 'acyl' to indicate substitution at nitrogen; this notation became standardized in organic chemistry literature and textbooks.
Originally 'acyl' referred generally to the radical or group derived from an acid; over time 'N-acyl' came to specifically denote an acyl group attached to a nitrogen atom (an N-substituted acyl derivative).
Meanings by Part of Speech
Noun 1
an N-acyl compound or derivative (a compound in which an acyl group is bound to nitrogen).
The synthesis yielded several N-acyls useful for further transformations.
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Verb 1
(chemistry) To introduce an acyl group onto a nitrogen atom; to convert (a nitrogen-containing compound) into its N-acyl derivative. (Verb form: to N-acylate)
The procedure N-acyls the amine under mild conditions.
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Adjective 1
having an acyl group attached to a nitrogen atom; used to describe compounds or substituents where the acyl moiety is bound to N.
The molecule is N-acyl at the amine, which alters its reactivity.
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Last updated: 2025/09/10 06:26