'human-influenced' is a compound of 'human' and 'influenced'. 'human' originates from Latin, specifically the word 'humanus', where the root related to 'of people' or 'humane', and 'influenced' derives from Latin 'influere' (via Old French 'influence'), where 'in-' meant 'into' and 'fluere' meant 'to flow'.

'human' changed from Old French word 'humain' and eventually became the modern English word 'human'. 'influence' changed from Latin word 'influere' through Old French 'influence' into Middle English 'influence'; the past-participle form 'influenced' was later used in modern English compounds such as 'human-influenced'.

Initially, 'influere' carried the image of 'flowing into' (and 'influence' had senses including astrological 'emanation'), but over time it shifted to the general sense 'to affect or have an effect on', which is the sense retained in 'influenced'. 'human' has consistently meant 'of or relating to people', so the compound's meaning became 'affected by people'.