'chest-pain-associated' originates from modern English as a compound of 'chest', 'pain', and the past-participle adjective 'associated'. The element 'associated' ultimately derives from Latin 'associare', where the prefix 'ad-' (to/toward) combined with 'socius' (companion/ally) produced a root meaning 'to join or unite with'.

'associated' entered English via Middle French 'associer' and Late Latin 'associare'; 'pain' comes via Old French 'peine' from Latin 'poena' (originally 'punishment' and later 'suffering'); 'chest' is from Old English 'cest' (body trunk). These elements combined in modern medical and technical English to form compound descriptors such as 'chest-pain-associated'.

Each element retained a stable core meaning (body trunk, physical suffering, and 'joined/related'), so the compound's meaning developed transparently: initially describing things 'joined with chest pain' and evolving into the clinical descriptor 'associated with chest pain'.