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English

autoregulation

|au-to-re-gu-la-tion|

C1

🇺🇸

/ˌɔːtoʊˌrɛɡjəˈleɪʃən/

🇬🇧

/ˌɔːtəʊˌrɛɡjʊˈleɪʃən/

self-control or self-adjustment of a system

Etymology
Etymology Information

'autoregulation' originates from English, formed by combining the prefix 'auto-' (from Greek 'autos' meaning 'self') with 'regulation' (from Latin 'regula'/'regulare' meaning 'rule' or 'to make straight').

Historical Evolution

'regulation' came into English via Latin 'regulatio' and Old French forms (e.g. 'regulation'), ultimately from Latin 'regula' ('rule'); the prefix 'auto-' comes from Greek 'autos' ('self') and entered English as a combining form. The compound 'autoregulation' developed in modern scientific English (primarily 19th–20th century) by joining these elements.

Meaning Changes

Originally 'regulation' referred to a rule or the act of keeping to a rule; over time it came to mean the act of controlling or adjusting a system. 'Autoregulation' specifically evolved to mean 'self-directed control or adjustment' in scientific contexts.

Meanings by Part of Speech

Noun 1

the process by which an organism, organ, or physiological system maintains stable internal conditions by adjusting its own functions (a form of self-regulation/homeostasis).

Cerebral autoregulation keeps brain blood flow relatively constant despite fluctuations in systemic blood pressure.

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Noun 2

in engineering and control theory, automatic adjustment of a device or system's parameters by internal mechanisms rather than by external control.

The power supply uses autoregulation to maintain a steady output voltage under varying loads.

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Noun 3

in molecular biology, a regulatory mechanism in which a gene product (such as a protein) regulates the expression of its own gene.

Many transcription factors show autoregulation, binding to their own promoter to increase or decrease expression.

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Last updated: 2025/11/28 08:48