'nonatopic' originates from Modern English formation combining the prefix 'non-' (from Old English 'nān' and Latin 'non' meaning 'not') with 'atopic', which ultimately derives from Greek 'atopos' where 'a-' meant 'not' and 'topos' meant 'place'.

'atopic' came from Greek 'atopos' -> Late Latin/medical coinage 'atopicus' -> English 'atopic' in modern medical usage; 'nonatopic' was formed in Modern English by prefixing 'non-' to 'atopic' to indicate the absence of atopy.

Initially, 'atopos' meant 'out of place'; over time 'atopic' specialized in medicine to mean 'relating to atopy (a predisposition to allergic reactions)'; 'nonatopic' now means 'not showing atopy'.