immunoresponsive
|ɪ-mjuː-noʊ-rɪ-ˈspɑːn-sɪv|
🇺🇸
/ɪˌmjuːnoʊrɪˈspɑːnsɪv/
🇬🇧
/ɪˌmjuːnəʊrɪˈspɒnsɪv/
responds to immune stimuli
Etymology
'immunoresponsive' is built from the combining form 'immuno-' and the adjective 'responsive'. 'Immuno-' originates from Latin, specifically the word 'immunis', where 'immunis' meant 'exempt, free (from public service)'. 'Responsive' ultimately comes from Latin 'respondere'.
'immuno-' developed from Latin 'immunis' into Medieval/Modern scientific combining forms (e.g. 'immune', 'immunity'), while 'responsive' comes from Latin 'respondere' → Old French/Anglo-Norman → Middle English 'responden'/'responsive'. The compound 'immunoresponsive' arose in modern biomedical English to describe a property relating to immune responses.
Originally 'immunis' meant 'exempt' and 'respondere' meant 'to answer/pledge'; over time 'immune' came to mean 'protected from disease' and 'responsive' to mean 'able to respond', and together the compound evolved to mean 'showing or producing an immune response'.
Meanings by Part of Speech
Adjective 1
capable of eliciting or producing an immune response (i.e., able to provoke activity of the immune system).
The candidate vaccine was immunoresponsive in preclinical trials, generating measurable antibody titers in all test animals.
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Adjective 2
able to respond to stimuli from the immune system (i.e., cells, tissues, or organisms that show a response when exposed to immune signals).
Tumor-infiltrating lymphocytes were highly immunoresponsive after checkpoint blockade therapy.
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Last updated: 2025/10/01 10:38