Langimage
English

apyrases

|a-py-ra-ses|

C2

/əˈpaɪreɪz/

(apyrase)

enzyme that breaks down ATP/ADP

Base FormPlural
apyraseapyrases
Etymology
Etymology Information

'apyrase' originates from modern scientific coinage (New Latin/Modern English), combining the prefix 'a-' (from Greek, meaning 'not' or 'without'), the element 'pyr-' (from 'pyrophosphate', referring to phosphate groups), and the suffix '-ase' (from French/Modern Latin, used to form enzyme names).

Historical Evolution

'apyrase' was coined in 20th-century biochemical literature as a name for enzymes that break down di- and triphosphate nucleotides; it is a modern technical formation rather than a word that passed through Old or Middle English stages.

Meaning Changes

Initially coined to denote an enzyme acting on (pyro)phosphate-type substrates, it has come to be used more specifically for enzymes hydrolyzing ATP and ADP to AMP and inorganic phosphate.

Meanings by Part of Speech

Noun 1

plural form of 'apyrase'.

Apyrases are commonly studied in insect saliva because they prevent platelet aggregation.

Noun 2

enzymes that hydrolyze nucleotide tri- and diphosphates (such as ATP and ADP) to AMP and inorganic phosphate; they are found in many organisms and, for example, secreted by blood-feeding animals to inhibit platelet aggregation.

Researchers purified several apyrases from mosquito saliva to study how they block blood clotting.

Synonyms

Last updated: 2025/09/18 03:25