'antiurolithic' originates from Neo-Latin and modern medical coinage, combining the Greek-derived elements 'anti-' (meaning 'against'), 'ouron' (meaning 'urine'), and 'lithos' (meaning 'stone').

'urolith' developed via New Latin 'urolithus' from Greek 'ouron' + 'lithos'; the adjective 'antiurolithic' was formed in modern medical English by prefixing 'anti-' and adding the adjectival suffix '-ic'.

Initially it meant 'acting against urinary stones' and over time has remained a specialized medical term meaning 'preventing the formation of urinary calculi'.