'antipsoric' originates from Greek elements: the prefix 'anti-' meaning 'against' and 'psōra' (ψῶρα) meaning 'itch' or 'scab'; the compound denotes something acting against psora.

'antipsoric' was coined in early 19th-century medical/homeopathic discourse (notably in writings by Samuel Hahnemann and contemporaries), formed by combining 'anti-' with 'psoric' (from Greek 'psōra'); the term entered English usage via German and Latin discussions of homeopathy.

Initially it meant 'against psora' specifically within homeopathic theory; over time it has remained a specialized term largely confined to homeopathic and historical medical contexts, retaining the core sense of opposing psora.