'antimedication' originates from Modern English, specifically the prefix 'anti-' (from Greek 'anti') meaning 'against' and the noun 'medication' (from Latin 'medicatio') meaning 'treatment; medical care'.

'medication' derives from Latin 'medicatio' via Old French 'medicacion' and Middle English 'medicacioun', eventually becoming modern English 'medication'. The prefix 'anti-' comes from Greek 'anti' and entered English usage via classical and Medieval Latin forms, later productive in Modern English compounds such as 'anti-'. Together they formed the compound 'antimedication' in recent English usage.

Initially the components meant 'against' + 'treatment'; the compound has remained essentially compositional, meaning 'against medication' or 'opposed to the use of medications'.