antifibrinolytic
|an-ti-fi-bri-no-lyt-ic|
🇺🇸
/ˌæn.ti.faɪ.brɪˈnɑː.lɪ.tɪk/
🇬🇧
/ˌæn.ti.faɪ.brɪˈnɒl.ɪ.tɪk/
against fibrin breakdown
Etymology
'antifibrinolytic' originates from Modern English formation, combining the prefix 'anti-' (from Greek 'anti-' meaning 'against') with 'fibrinolytic' (from 'fibrin' + 'lysis' + suffix '-lytic').
'fibrinolytic' developed from 'fibrinolysis' (New Latin/Modern formation from 'fibrin' + Greek 'lysis' meaning 'loosening' or 'breaking'), with the adjectival suffix '-ic'; 'antifibrinolytic' was formed by adding the prefix 'anti-' to this adjective to convey opposition to fibrinolysis.
Initially formed to mean 'against fibrinolysis' in a literal morphological sense; it has come to be used specifically in medicine to mean 'preventing or inhibiting the breakdown of fibrin (thereby reducing bleeding)'.
Meanings by Part of Speech
Noun 1
a substance or drug that inhibits fibrinolysis; an agent used to reduce bleeding by preventing the breakdown of fibrin.
Tranexamic acid is a commonly used antifibrinolytic in trauma and surgery.
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Adjective 1
preventing or inhibiting fibrinolysis (the breakdown of fibrin in blood clots).
The surgeon administered an antifibrinolytic drug to reduce bleeding during the procedure.
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Last updated: 2025/10/28 22:38