'antifibrinolysis' is formed from the prefix 'anti-' (from Greek anti- meaning 'against') combined with 'fibrinolysis' (from 'fibrin' + '-lysis').

'fibrinolysis' is a modern medical formation (20th century) from 'fibrin' (from Latin/Greek roots meaning 'fiber') + Greek 'lysis' meaning 'loosening' or 'dissolution'; 'antifibrinolysis' was later created by adding 'anti-' to indicate opposition to fibrinolysis.

Initially a straightforward technical formation meaning 'opposition to fibrinolysis,' the term has retained that core medical meaning and is used to describe drugs, interventions, or physiological states that prevent fibrin breakdown.