'amygdalin-based' originates from English, specifically the noun 'amygdalin' combined with the adjectival element '-based' (from 'base'), where 'amygdalin' traces to Neo-Latin 'amygdalina' and Greek 'amygdalē' meaning 'almond', and 'base' comes via Old French/Latin 'basis' meaning 'foundation'.

'amygdalin' changed from Neo-Latin 'amygdalina' (itself from Greek 'amygdalē') and eventually became the modern English noun 'amygdalin'; 'base' came into English via Old French 'base' from Late Latin/Greek 'basis', and the compound adjective form '-based' developed in modern English to mean 'having X as a base' (e.g., 'sugar-based').

Initially, 'amygdalin' referred specifically to a substance associated with almonds and similar seeds; 'base' originally meant 'foundation' or 'step' in older usage. Over time the compound 'amygdalin-based' has come to mean 'having amygdalin as its basis, source, or principal constituent.'