'amide-bound' originates from English compounding of the noun 'amide' and the past participle/adjective 'bound'. 'amide' itself originates from 19th-century French 'amide' (and German 'Amid'), ultimately coined from New Latin 'amide' related to 'ammonia', where the suffix '-ide' indicated a derived radical. 'bound' is from Old English 'bounden' (past participle of 'bind').

'amide' changed from German 'Amid' and French 'amide' (19th century chemical nomenclature) and entered English chemical vocabulary as 'amide'; 'bound' comes from Old English 'bindan' > past participle 'bounden' > modern 'bound'. The compound 'amide-bound' formed in modern scientific English to describe something linked by an amide bond.

Initially, 'amide' denoted a chemical radical related to ammonia derivatives; over time it came to name the specific functional group 'amide'. Combined with 'bound', the compound now specifically means 'attached via an amide bond'.