'vasoneurotic' is a modern compound formed in English from the combining elements 'vaso-' and 'neurotic'. 'vaso-' ultimately comes from Latin 'vas' meaning 'vessel', and 'neuro-' comes from Greek 'neûron' meaning 'nerve'; the suffix '-tic' comes from Greek '-tikos' meaning 'pertaining to'.

'vasoneurotic' was formed by analogy with medical compounds in the 19th to early 20th century (e.g., 'vasomotor', 'neurotic'), combining 'vaso-' + 'neurotic' to describe disorders involving both vessels and nerves; it did not evolve from a single earlier English word but from these classical combining forms.

Initially the elements referred separately to 'vessel' and 'nerve-related' concepts; over time the compound came to denote a specific clinical idea of dysfunction involving both blood vessels and nervous control (i.e., vasoneurosis or vasomotor neurotic disturbance).