'vasculoblast' originates from Neo-Latin and Greek, specifically the Latin word 'vasculum' where 'vascul-' meant 'small vessel', and the Greek word 'blastos' where 'blastos' meant 'bud' or 'germ'.

'vasculoblast' was coined in modern scientific (Neo-Latin) usage from the combination of Latin 'vasculum' and Greek 'blastos', forming terms like 'vasculoblastus' in scholarly texts and later adopted into English as 'vasculoblast'.

Initially the roots conveyed the sense 'small vessel bud' (a bud or germ of a vessel), and over time this evolved into the specialized biological meaning 'a precursor cell that forms blood vessels'.