'urease-enhancing' originates from Modern English, specifically a compound of 'urease' + 'enhancing', where 'urease' denotes the enzyme that hydrolyzes urea and 'enhancing' is the present participle of 'enhance' meaning 'to increase or improve'.

'urease' itself was formed by combining 'urea' (the compound name) with the enzyme suffix '-ase' (a convention in biochemical nomenclature coined in the late 19th century); 'enhance' came into English via Old French 'enhauncer' (from Late Latin/French roots) and developed into the modern verb 'enhance'. The compound 'urease-enhancing' is a contemporary technical formation used in scientific writing.

Initially components referred separately to the chemical substrate ('urea') and the general verb 'enhance'; together as a compound they have come to be used specifically to describe agents or properties that increase urease enzyme activity, a specialized technical sense that emerged with biochemical research.