upregulated
|up-reg-u-lat-ed|
C1
🇺🇸
/ˈʌpˌrɛɡjəˌleɪtɪd/
🇬🇧
/ˈʌpˌrɛɡjʊˌleɪtɪd/
(upregulate)
increase regulation or activity
Etymology
Etymology Information
'upregulate' is formed in English from the prefix 'up-' meaning 'increase' and 'regulate' meaning 'to control or adjust.'
Historical Evolution
'upregulate' was coined in modern English by combining 'up-' and 'regulate,' and 'upregulated' is its past tense and past participle form.
Meaning Changes
Initially, it meant 'to increase the regulation or expression (of a gene, protein, etc.),' and this meaning has remained consistent in scientific usage.
Meanings by Part of Speech
Verb 1
past tense or past participle form of 'upregulate'.
The gene was upregulated in response to the treatment.
Last updated: 2025/07/28 05:43