'uninucleated' is formed from the prefix 'uni-' (from Latin 'unus' meaning 'one') + 'nucleus' (Latin 'nucleus' meaning 'kernel, core') with the adjective-forming suffix '-ate'.

'uni-' (from Latin 'unus') and 'nucleus' (Latin) were combined in modern scientific English to form 'uninucleate' (adjective), and the adjectival/past form 'uninucleated' developed in technical usage to describe cells having one nucleus.

Initially coined in scientific contexts to mean 'having a single nucleus'; this core meaning has been retained in modern usage.