'uni-centric' originates from Latin and Greek: the prefix 'uni-' ultimately from Latin 'unus' where 'unus' meant 'one', and the element 'centric' from Greek 'kentron' (through Late Latin/medieval formations) where 'kentron' meant 'center'.

'uni-centric' was formed by combining the Latin-derived prefix 'uni-' with the Greek-derived combining form 'centric' (compare French/Latin compounds and later English coinages like 'monocentric'), producing the modern English adjective 'uni-centric' (also seen as 'unicentric').

Initially it literally meant 'having one center' and over time has retained that core sense, being used in technical, urban-planning, and theoretical contexts to describe single-centered structures or systems.