'titration-based' is a compound word formed from 'titration' and the suffix '-based', where 'titration' comes from the process of measuring concentration in chemistry, and '-based' means 'founded on or derived from'.

'titration' comes from the French word 'titrer' meaning 'to determine the concentration of', and '-based' is a common English suffix. The compound 'titration-based' emerged in modern scientific English to describe methods or processes that use titration as their foundation.

Initially, 'titration-based' specifically referred to methods using titration in chemistry, but it is now used more broadly in scientific and analytical contexts.