Langimage
English

tissue-incompatibility

|tis-sue-in-com-pat-i-bil-i-ty|

C2

🇺🇸

/ˈtɪʃuː ɪnˌkəmˌpætəˈbɪlɪti/

🇬🇧

/ˈtɪʃjuː ɪnˌkɒmpəˈbɪlɪti/

mismatch between tissues

Etymology
Etymology Information

'tissue-incompatibility' is a compound of 'tissue' and 'incompatibility'. 'tissue' originates from Old French, specifically the word 'tissu', where the stem (from Latin 'texere') meant 'to weave'. 'incompatibility' originates from Medieval Latin 'incompatibilitas', where the prefix 'in-' meant 'not' and 'compatibilis' meant 'able to exist together'.

Historical Evolution

'tissue' entered Middle English from Old French 'tissu' and developed into the modern English 'tissue'. 'incompatibility' developed from Medieval Latin 'incompatibilitas' through Old French 'incompatibilité' into modern English 'incompatibility'. The compound term 'tissue-incompatibility' arose in medical usage (histocompatibility/transplantation literature) in the 19th–20th centuries.

Meaning Changes

Initially, 'tissue' referred to 'that which is woven' and 'incompatibility' broadly meant 'not able to co-exist'. Over time, the compound came to be used in medicine to mean specifically an immunological mismatch between tissues that can cause transplant rejection.

Meanings by Part of Speech

Noun 1

lack of compatibility between tissues (such as between donor and recipient) that can trigger an immune response and cause transplant rejection; an immunological mismatch of tissue antigens (e.g., HLA).

Tissue-incompatibility between the donor and recipient led to acute rejection of the transplant.

Synonyms

Antonyms

Last updated: 2026/01/01 19:05