'systematically-modified' originates from the combination of 'systematic' and 'modified', where 'systematic' comes from the Greek 'systēmatikos', meaning 'pertaining to a system', and 'modified' from the Latin 'modificare', meaning 'to measure or limit'.

'Systematic' evolved from the Greek 'systēmatikos' through Latin 'systematicus', while 'modified' transformed from Latin 'modificare' through Old French 'modifier'.

Initially, 'systematic' meant 'pertaining to a system', and 'modified' meant 'to measure or limit'. Over time, 'systematically-modified' came to mean 'altered in a methodical manner'.