'systematically-altered' originates from the combination of 'systematic' and 'altered'. 'Systematic' comes from the Greek word 'systēmatikos', meaning 'pertaining to a system', and 'altered' is derived from the Latin word 'alterare', meaning 'to change'.

'systematically-altered' evolved from the combination of 'systematic' and 'altered', which were used separately in English before being combined to describe a methodical change.

Initially, 'systematic' meant 'pertaining to a system', and 'altered' meant 'changed'. Together, they evolved to describe a change done in an organized manner.