'strain-associated' is a compound word formed by combining 'strain' and 'associated'. 'Strain' originates from Middle English 'streine', from Old French 'estreindre', from Latin 'stringere', meaning 'to bind tightly'. 'Associated' comes from Latin 'associatus', past participle of 'associare', meaning 'to unite or join'.

'Strain' evolved from the Latin 'stringere' through Old French 'estreindre', while 'associated' evolved from Latin 'associare'. The combination of these words in modern English forms 'strain-associated'.

Initially, 'strain' referred to a lineage or breed, while 'associated' meant 'joined or connected'. Together, they now describe a connection to a specific strain, often in scientific contexts.