'spider-related' is a modern English compound formed from the noun 'spider' and the adjective 'related' (the past participle of 'relate').

'spider' ultimately comes from Old English (once written as forms like 'spīdre') meaning 'spinner' (from the verb 'to spin'), while 'related' comes from Latin 'relatus' (past participle of 'referre') via Old French and Middle English; the two elements were combined in Modern English to make the compound 'spider-related'.

The compound originally and still literally means 'having a relation to spiders'; its meaning has remained essentially the same as when the compound was formed.