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English

self-reactivity

|self-re-ac-ti-vi-ty|

C2

/ˌsɛlf.riːækˈtɪvɪti/

reaction to oneself

Etymology
Etymology Information

'self-reactivity' is formed in modern English by combining 'self' (Old English 'self') and 'reactivity' (from 'react' + suffix '-ivity'). 'react' ultimately derives from Latin elements 're-' meaning 'again' and 'agere' meaning 'to do/act'.

Historical Evolution

'react' developed from Latin components into Medieval Latin forms (e.g. 'reactus'), passed through Old French/late Latin reflexive forms (e.g. French 'réagir'), and entered English as 'react'; 'reactivity' was formed by adding the noun-forming suffix '-ivity', and 'self-reactivity' is a modern compound combining 'self' + 'reactivity'.

Meaning Changes

Originally 'reactivity' broadly meant 'the capacity to respond to a stimulus'; over time, in biomedical contexts the compound 'self-reactivity' came to denote specifically 'reactivity directed against one's own tissues or antigens'.

Meanings by Part of Speech

Noun 1

in immunology, the tendency or capacity of immune cells (e.g., T cells, B cells) to respond to the body's own antigens, potentially leading to autoimmunity.

High self-reactivity of T cells is associated with the development of autoimmune disease.

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Noun 2

a more general sense: the tendency of an organism or system to react to its own components, signals, or actions (used in psychology or systems theory).

Her heightened self-reactivity caused her to misinterpret normal bodily sensations as signs of illness.

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Last updated: 2025/10/09 14:26