'seam-related' is a compound formed from English 'seam' and 'related'. 'Seam' comes from Old English 'sēam' (via Proto-Germanic '*saumaz'), and 'related' is the past participle of 'relate', ultimately from Latin 'relatus'.

'Seam' developed from Old English 'sēam' (compare Old High German 'saum') into the modern English 'seam'. 'Related' comes from Latin 'relatus' (past participle of 'referre'/'relare'), passed into Middle English via Old French and English verb forms to become the adjective 'related'. The compound 'seam-related' is a modern English formation combining those elements.

Initially, the elements meant 'a line where materials are joined' (seam) and 'connected' (related); over time the compound has been used in technical and descriptive contexts to mean 'connected with or caused by a seam'.