'revascularization' originates from Modern English, specifically formed from the prefix 're-' (from Latin 're-' meaning 'again'), the adjective 'vascular' (from Latin 'vasculum' < 'vas' meaning 'vessel'), and the noun-forming suffix '-ization' (from French/Latin-derived English meaning 'process or action').

'revascularization' was built from the verb forms 'revascularize'/'revascularise' (formed in modern medical English) and then used as the noun 'revascularization' to denote the process; its elements trace back through New Latin/Modern Latin medical formation rather than to an Old English ancestor.

Initially the components simply meant 'to make vascular again' (i.e., 'again' + 'vessel-related'), and over time the combined term acquired the specific medical sense 'the restoration of blood supply to tissue' used in contemporary medicine.