Langimage
English

proarrhythmic

|pro-ar-rhyth-mic|

C2

🇺🇸

/ˌproʊəˈrɪðmɪk/

🇬🇧

/ˌprəʊəˈrɪðmɪk/

causing abnormal heart rhythm

Etymology
Etymology Information

'proarrhythmic' originates from the prefix 'pro-' (Latin 'pro', meaning 'for' or 'forward') combined with 'arrhythmic', which comes from Greek 'arrhythmia' ('a-' meaning 'not' + 'rhythmos' meaning 'rhythm').

Historical Evolution

'arrhythmia' entered New Latin from Greek 'arrhythmia', then passed into English as 'arrhythmia' with the adjective form 'arrhythmic'; in modern medical English the prefix 'pro-' was attached to form 'proarrhythmic'.

Meaning Changes

The element 'arrhythmia' originally denoted 'lack of rhythm' in Greek, and over time its medical sense became 'abnormal heart rhythm'; 'proarrhythmic' is a modern formation meaning 'promoting or causing abnormal heart rhythms'.

Meanings by Part of Speech

Adjective 1

tending to cause, provoke, or aggravate cardiac arrhythmias; used especially of drugs or interventions that increase the risk of abnormal heart rhythms.

The drug was withdrawn after being found to be proarrhythmic in some patients.

Synonyms

arrhythmogenicpro-arrhythmic

Antonyms

Last updated: 2025/10/16 01:10