'pro-orgasmic' is a modern compound formed from the prefix 'pro-' (from Latin 'pro', meaning 'for' or 'in favor of') and 'orgasmic' (relating to 'orgasm').

'orgasm' originates from Greek 'orgasmos' (ὀργασμός), passed into Latin and then into English as 'orgasm'; the adjective 'orgasmic' was later formed by adding the suffix '-ic'. The prefix 'pro-' has long been used in English to form compounds meaning 'in favor of', and the compound 'pro-orgasmic' is a recent coinage using that productive pattern.

Originally 'orgasmos' in Greek referred to swelling or excitement; over time it came to denote sexual climax, and 'pro-orgasmic' has come to mean 'in favor of or promoting orgasm'.