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pro-drug

|pro-drug|

C1

🇺🇸

/ˈproʊˌdrʌɡ/

🇬🇧

/ˈprəʊˌdrʌɡ/

inactive precursor

Etymology
Etymology Information

'pro-drug' originates from the prefix 'pro-' meaning 'before' and 'drug', indicating a substance that becomes active after a metabolic process.

Historical Evolution

The term 'pro-drug' was coined in the 20th century to describe drugs that require metabolic conversion to become active.

Meaning Changes

Initially, it referred to any substance that needed conversion to become active, and this meaning has remained consistent.

Meanings by Part of Speech

Noun 1

a compound that, after administration, is metabolized into a pharmacologically active drug.

The pro-drug is converted into its active form in the liver.

Synonyms

Antonyms

Last updated: 2025/02/12 00:03