'peptide-bonded' is a compound formed in Modern English from the scientific element 'peptide' and the noun 'bond.' 'Peptide' ultimately derives from Greek 'peptid-' (from 'peptos'), where 'peptid-' meant 'digested' (used in modern chemistry to name short amino-acid chains), and 'bond' comes from Old English/Middle English roots related to 'band'/'bond', where the root meant 'that which binds'.

'peptide' entered modern scientific vocabulary (via German 'Peptid' and New Latin formations) from Greek 'peptid-'; 'bond' developed from Old English/Middle English words for a tie or binding; the compound 'peptide-bond' was coined in biochemical contexts to name the chemical link between amino acids, and the adjectival/past participle form 'peptide-bonded' was formed by adding the English suffix '-ed'.

Initially the Greek root related to 'digested' or 'cooked' material; over time 'peptide' came to be used specifically for short chains of amino acids, and combined with 'bond' it now denotes the specific chemical link between amino acids; 'peptide-bonded' therefore means 'joined by such peptide bonds'.