'ozone-resistant' originates as a Modern English compound of the noun 'ozone' and the adjective 'resistant'. 'Ozone' itself was coined in the 1840s from Greek 'ozein' (meaning 'to smell') via scientific usage, while 'resistant' comes from Latin 'resistere' (re- + sistere).

'ozone' entered English in the 19th century from French 'ozone', ultimately from Greek 'ozein'; 'resistant' derives from Latin 'resistere' → Old French/Middle English developments that produced the English adjective 'resistant'. The compound 'ozone-resistant' arose in technical and industrial English in the 20th century to describe materials that withstand ozone.

Initially 'ozone' named a substance associated with a smell and 'resistant' meant 'to stand back' or 'oppose'; together the compound came to mean 'able to withstand the deteriorating or reactive effects of ozone' in modern technical usage.