orthotopic
|or-tho-top-ic|
🇺🇸
/ˌɔrθəˈtɑpɪk/
🇬🇧
/ˌɔːθəˈtɒpɪk/
correct (normal) place
Etymology
'orthotopic' originates from Greek, specifically the word 'orthotopos', where 'ortho-' meant 'straight' or 'correct' and 'topos' meant 'place'.
'orthotopic' changed from the Greek word 'orthotopos' into Late Latin/New Latin medical formations such as 'orthotopicus' and eventually entered modern English as 'orthotopic' via medical Latin usage.
Initially, it meant 'correct place' in Greek, but over time it evolved into its current medical sense of 'located in or relating to the normal anatomical position', especially for transplants.
Meanings by Part of Speech
Adjective 1
located at or relating to the normal or correct anatomic position.
The tumor was found in an orthotopic location, adjacent to the organ's usual site.
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Adjective 2
describing a transplant placed in the recipient's normal anatomical site (as opposed to a heterotopic transplant).
An orthotopic liver transplant places the donor liver in the same anatomical site as the original liver.
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Last updated: 2025/10/22 20:09