'opioid' originates from 'opium', specifically the word 'opium', where 'opos' meant 'juice' in Greek, and 'connected' comes from Latin 'connectere', where 'con-' meant 'together' and 'nectere' meant 'to bind'.

'opioid' evolved from the Greek word 'opos' to the modern English 'opioid', and 'connected' transformed from the Latin 'connectere' to the modern English 'connected'.

Initially, 'opioid' referred to substances derived from opium, but now it includes synthetic drugs with similar effects. 'Connected' has maintained its meaning of being linked or associated.