'non-spermatogenic' originates from English combining the prefix 'non-' (from Latin 'non' meaning 'not') and 'spermatogenic', which comes from Greek 'sperma' (σπέρμα) meaning 'seed' (here 'sperm') and Greek 'genēs' (γένης) meaning 'born' or 'producing'.

'spermatogenic' was formed in modern medical terminology from the combining form 'spermato-' (from Greek 'sperma') plus the suffix '-genic' (from Greek roots related to production); later, the negative prefix 'non-' was attached in English to create 'non-spermatogenic'.

Originally, 'spermatogenic' meant 'producing seed/sperm'; the addition of the prefix 'non-' yields the current meaning 'not producing sperm'.