'node-related' is a modern English compound formed from the noun 'node' + the past-participial/adjectival form 'related' (literally 'related to a node').

'node' originates from Latin 'nodus' meaning 'knot'; it passed into Old French/Medieval Latin and Middle English as 'node' and developed senses such as 'a knot' and later 'a point or junction' (especially in scientific and technical usage). 'related' derives from Latin 'relatus', the past participle of 'referre' via Old French 'relater' and Middle English 'relaten', coming to mean 'connected' or 'having a relation'. The compound 'node-related' is a straightforward modern coinage combining these elements.

Initially, 'node' primarily meant 'knot' in Latin, but over time it acquired the modern technical sense of 'a point/junction in a network or structure'; 'related' originally meant 'carried back' or 'reported' (from Latin) and evolved to mean 'connected' or 'having a relation', which together yield the current meaning 'connected to or concerning a node'.