mononuclear-dominant
|mo-no-nu-clear---dom-i-nant|
🇺🇸
/ˌmoʊnoʊˈnuːklər ˈdɑːmɪnənt/
🇬🇧
/ˌmɒnəʊˈnjuːklə ˈdɒmɪnənt/
predominance of mononuclear cells
Etymology
'mononuclear-dominant' is a compound formed from 'mononuclear' and 'dominant'. 'mononuclear' itself derives from Greek 'monos' meaning 'single' combined with Latin 'nucleus' meaning 'kernel/core'; 'dominant' originates from Latin 'dominant-' (from 'dominare') meaning 'to rule' or 'to be master of'.
'mononuclear' was coined in modern scientific usage by combining the Greek/Neo-Latin elements 'mono-' + 'nuclear' in the 19th century to describe single-nucleus cells; 'dominant' entered English via Latin ('dominans') and Old French and has meant 'having superiority' since Middle English. The compound form 'mononuclear-dominant' developed in medical and pathological descriptions to denote cell-type predominance.
Individually, 'mononuclear' originally meant 'having a single nucleus' and 'dominant' meant 'ruling' or 'prevailing'; combined in clinical language the compound evolved to mean 'predominantly composed of mononuclear cells' rather than a literal ruling sense.
Meanings by Part of Speech
Noun 1
a condition or pattern in which mononuclear cells predominate.
Mononuclear-dominant is commonly reported in histology reports of viral infections and certain chronic inflammatory conditions.
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Adjective 1
predominantly composed of mononuclear cells (e.g., lymphocytes, monocytes/macrophages); used especially to describe an inflammatory infiltrate or cellular pattern where mononuclear cells outnumber polymorphonuclear cells.
The biopsy revealed a mononuclear-dominant infiltrate, which is more typical of viral or chronic inflammation than of acute bacterial infection.
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Last updated: 2025/12/14 23:14