Langimage
English

monogenic

|mon-o-gen-ic|

C1

🇺🇸

/ˌmoʊnoʊˈdʒɛnɪk/

🇬🇧

/ˌmɒnəˈdʒɛnɪk/

originating from a single gene

Etymology
Etymology Information

'monogenic' originates from Greek, specifically the word 'monogenēs', where 'monos' meant 'single' and 'genēs' (from 'genos') meant 'birth, origin, kind'.

Historical Evolution

'monogenēs' passed into New Latin/Modern scientific formation as 'monogenetic/monogenic' and was adopted into English in scientific usage to form 'monogenic'.

Meaning Changes

Initially, the Greek root referred broadly to 'originating from a single source' (birth/origin); in modern scientific English it evolved to the narrower sense of 'originating from or determined by a single gene'.

Meanings by Part of Speech

Adjective 1

caused by or determined by a single gene; describing a trait, disorder, or characteristic that is controlled by one gene.

Cystic fibrosis is a monogenic disorder caused by mutations in the CFTR gene.

Synonyms

Antonyms

Last updated: 2025/09/18 05:40