'mitochondria-related' originates from Modern English, specifically formed from the noun 'mitochondria' + the adjective 'related', where 'mitochondria' ultimately comes from Greek 'mitos' meaning 'thread' and 'chondrion' meaning 'granule'.

The scientific term 'mitochondrion' was coined in the late 19th century (from German/Modern scientific usage) from Greek roots; English adopted the plural 'mitochondria', and modern English formed compounds such as 'mitochondria-related' by combining that plural noun with 'related'.

Initially the Greek-derived element referred to the literal 'thread-like granules' observed microscopically; over time it became the standard name for the organelle, and compounds like 'mitochondria-related' evolved to mean 'pertaining to those organelles'.