'miscreation' originates from English, formed by combining the prefix 'mis-' (Old English prefix meaning 'wrong(ly)') with 'creation' from Latin 'creatio' (from 'creare', meaning 'to create').

'miscreation' was formed in Middle/Late Middle English by joining 'mis-' and 'creation'; attestations appear from early modern English usage (16th–17th century) where it described faulty or monstrous products of creation.

Initially it conveyed the idea of a 'wrongful or faulty act of creating' or a 'badly made thing'; over time it came to be used more often for 'a malformed or monstrous creature' and, figuratively, 'an abominable person.'