'male-biased' originates from modern English as a compound of 'male' and 'biased', where 'male' ultimately comes from Old French 'masle' (from Latin 'masculus') meaning 'male' and 'biased' derives from the noun 'bias' meaning 'a slant or inclination'.

'male' entered English via Old French 'masle' from Latin 'masculus'; 'bias' entered Middle English from Old French 'biais' (meaning 'slant'), and 'biased' developed as the adjective form in English; the compound 'male-biased' was formed in modern English by combining these elements to describe a preference toward men.

Initially the components referred separately to 'male' (an adult man) and to a 'slant' or inclination; over time they combined to form 'male-biased', meaning 'showing a preference or advantage for men', a usage that became common in social and academic contexts.