'lesion' originates from Latin, specifically the word 'laesio,' where 'laedere' meant 'to injure or hurt.'

'laesio' transformed into the Old French word 'lesion,' and eventually became the modern English word 'lesion' through Middle English.

Initially, it meant 'an injury or hurt,' but over time it evolved into its current meaning of 'a region in an organ or tissue that has suffered damage.'