'irreproducible' originates from the prefix 'ir-' meaning 'not' and the word 'reproducible', which comes from Latin 'reproducere', where 're-' meant 'again' and 'producere' meant 'to lead forth'.

'reproducere' transformed into the French word 'reproduire', and eventually became the modern English word 'reproduce', with 'irreproducible' forming as a negation.

Initially, it meant 'not able to be produced again', and this meaning has largely remained the same in modern usage.