'irremediably' originates from Latin, specifically the word 'irremediabilis,' where 'ir-' meant 'not' and 'remediabilis' meant 'able to be remedied.'

'irremediabilis' transformed into the French word 'irremédiable,' and eventually became the modern English word 'irremediable' through Middle English.

Initially, it meant 'not able to be remedied,' and this meaning has largely remained the same in modern usage.