'homochromia' originates from Greek, specifically from the elements 'homo-' (from Greek 'hómos') meaning 'same' and 'chroma' (Greek 'chrôma') meaning 'color'.

'homochromia' was formed in modern scientific/medical usage by combining Greek roots and was adopted into Neo-Latin and then English scientific vocabulary (appearing in 19th-century medical literature and later).

Initially it meant 'the state of being the same color,' and over time this core meaning has remained stable, used specifically in biological and medical descriptions.