'histological' originates from Greek via Modern Latin/Neo-Latin, specifically from the Greek root 'histos' meaning 'tissue' combined with '-logy' (from Greek 'logia') meaning 'study', with the adjectival suffix '-ical' added in English.

'histological' developed from the noun 'histology' (New Latin/English), which itself comes from Greek 'histos' + 'logia'; the adjective was formed in English by adding the suffix '-ical' to produce 'histological'.

Initially it meant 'pertaining to the study of tissues,' and over time this specialised meaning has been retained in modern usage to denote something related to tissue structure or histology.