'genomic' originates from New Latin/modern scientific English, specifically formed from the word 'genome' plus the suffix '-ic', where 'genome' meant 'complete set of genes' and '-ic' meant 'relating to'.

'genomic' developed from the modern scientific term 'genome'. The English 'genome' was influenced by German 'Genom' (coined by Hans Winkler in 1920), which itself was based on Greek 'genoma' (from 'genein', 'to beget'). The adjective 'genomic' was then formed in English by adding the adjectival suffix '-ic'.

Initially it meant 'relating to the genome' and, over the 20th and 21st centuries, its use broadened to cover technologies, data, and analyses related to genomes (e.g., genomic sequencing, genomic data).