'enzymic' originates from Modern English formation from the noun 'enzyme' plus the suffix '-ic', where 'enzyme' ultimately comes from Greek 'enzymon' (from 'en-' meaning 'in' and 'zyme' meaning 'leaven').

'enzymic' was formed in English by attaching the adjectival suffix '-ic' (from Greek/Latin use of '-ikos') to the borrowed scientific noun 'enzyme' (borrowed into English in the 19th century from German 'Enzym', from Greek 'enzymon'), producing the modern adjective 'enzymic'.

Initially it meant 'pertaining to or produced by enzymes', and this core meaning has remained largely unchanged in modern usage.